Long-term prostacyclin infusion to reduce pulmonary hypertension in a pediatric cardiac transplant candidate prior to transplantation

Pulmonary hypertension represents a significant risk factor for peri-operat ive death in patients undergoing cardiac transplantation. Heart-lung transp lantation is generally the only procedure available for patients whose pulm onary hypertension can not be reversed by conventional pharmacologic means. We present a pediatric patient with end-stage cardiac disease and refracto ry pulmonary hypertension who was treated with long-term intravenous prosta cyclin. This resulted in a significant enough improvement in her hemodynami cs to allow for successful cardiac transplantation alone.