Dk. Oh et al., Increased erythritol production in fed-batch cultures of Torula sp by controlling glucose concentration, J IND MIC B, 26(4), 2001, pp. 248-252
Citations number
16
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
The effect of glucose concentration on erythritol production by Torula sp,
was investigated, The maximum volumetric productivity of erythritol was obt
ained at an initial glucose concentration of 300 g l(-1) in batch culture.
The volumetric productivity was maximal at a controlled glucose concentrati
on of 225 g l(-1), reducing the lag time of the erythritol production. A fe
d-batch culture was established with an initial glucose concentration of 30
0 g l(-1) and with a controlled glucose concentration of 225 g l(-1) in med
ium containing phytic acid as a phosphate source, In this fed-batch culture
, a final erythritol production of 192 g l(-1) was obtained from 400 g l(-1
) glucose in 88 h. This corresponded to a volumetric productivity of 2.26 g
l(-1) h(-1) and a 48% yield.