Acute hemolysis and severe neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient heterozygotes

Authors
Kaplan, M Hammerman, C Vreman, HJ Stevenson, DK Beutler, E
Citation
M. Kaplan et al., Acute hemolysis and severe neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient heterozygotes, J PEDIAT, 139(1), 2001, pp. 137-140
Citations number
17
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
JOURNAL OF PEDIATRICS
ISSN journal
00223476 → ACNP
Volume
139
Issue
1
Year of publication
2001
Pages
137 - 140
Database
ISI
SICI code
0022-3476(200107)139:1<137:AHASNH>2.0.ZU;2-Z
Abstract
Two premature female infants had severe hyperbilirubinemia caused by hemoly sis. Both neonates were heterozygotes for the glucose-g-phosphate dehydroge nase Mediterranean mutation as determined by DNA analysis. Glucose-6-phosph ate dehydrogenase-deficient heterozygotes may be susceptible to the complic ations of this enzyme deficiency.