S. Cascio et al., Bacterial colonization of the prepuce in boys with vesicoureteral reflux who receive antibiotic prophylaxis, J PEDIAT, 139(1), 2001, pp. 160-162
Culture swabs were taken from the periurethral area of 59 consecutive uncir
cumcised boys with vesicoureteral reflux (WR) and 36 boys undergoing circum
cision. A pure growth of a uropathogen was isolated in 22 (37%) boys with V
OR who were receiving antibiotic prophylaxis and in 10 (28%) boys who under
went circumcision. Antibiotic prophylaxis in patients with VUR was not effe
ctive in reducing the bacterial colonization of the prepuce. We recommend c
ircumcision in boys, particularly infants with VUR, to reduce the risk of u
rinary tract infections.