Objective: The purpose of this study was to report a feasibility trial appr
oved by the Institutional Review Board for insertion of inferior vena cava
(IVC) filters with intravascular ultrasound (IVUS) guidance in the intensiv
e care unit.
Methods: Between October 1998 and May 2000, 26 patients (15 men, 11 women;
age range, 22-86 years; mean, 55 years) were enrolled. Eight patients (31%)
underwent prophylactic filter placement, and 18 patients (69%) had venous
thromboembolism (deep venous thrombosis = 16, pulmonary embolism = 2) with
contraindications to anticoagulation. A single groin puncture was used for
IVUS and filter placement. Location of major branch veins, thrombosis, and
caval diameter were readily demonstrated without the use of radiocontrast a
gents. Mapping of the IVC permitted assessment of ideal filter location. Po
stprocedure radiographs (25 of 26) were obtained to document filter positio
n. Seventeen of 26 had follow-up lower extremity duplex studies.
Results: Twenty-four (92%) of 26 patients underwent successful filter deplo
yment. The two other patients had filters subsequently placed by means of t
raditional fluoroscopic techniques. One femoral vein insertion site thrombo
sis resolved after a month. One patient experienced symptomatic caval throm
bosis thought to be caused by thrombus trapping 55 days after the procedure
. No pulmonary emboli occurred after filter placement. One patient's death
was unrelated to vena cava filter placement. The hospital charge for bedsid
e filters was $3623 compared with $4165 (P=.281) for fluoroscopic placement
.
Conclusion: Bedside insertion of an IVC filter with IVUS guidance is feasib
le and may be an effective alternative in the intensive care unit. No addit
ional costs were incurred in this small series. Protocol refinements should
reduce the incidence of complications. The results of this study support t
he need for further evaluation comparing it with standard techniques.