A guide to 17 beta-hydroxysteroid dehydrogenases

Authors
Adamski, J Jakob, FJ
Citation
J. Adamski et Fj. Jakob, A guide to 17 beta-hydroxysteroid dehydrogenases, MOL C ENDOC, 171(1-2), 2001, pp. 1-4
Citations number
38
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
MOLECULAR AND CELLULAR ENDOCRINOLOGY
ISSN journal
03037207 → ACNP
Volume
171
Issue
1-2
Year of publication
2001
Pages
1 - 4
Database
ISI
SICI code
0303-7207(20010122)171:1-2<1:AGT1BD>2.0.ZU;2-W
Abstract
17 beta -Hydroxysteroid dehydrogenases (17 beta -HSD) are pivotal in contro lling the biological potency of steroid hormones by catalyzing oxidation or reduction at position 17. Several 17 beta -HSDs may as well metabolize fur ther substrates including alcohols, bile acids. fatty acids and retinols. T his review summarizes recent progress in the field of 17 beta -HSD research provides an update of nomenclature. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.