Sphenoid sinusitis caused by clostridium perfringens

Anaerobic bacterial infections in chronic sinusitis are well described in l iterature. We present what is believed to be the first reported case of Clo stridium perfringens presenting as the causative pathogen in paranasal sinu sitis. This patient presented with severe headaches and, with CT and MRI fi ndings of unilateral sphenoid sinus opacification, with bone demineralizati on and intrasinus calcification. This patient responded to endoscopic debri dement and long-term antibiotics without sequelae.