Clinical appraisal of patients and detection of serum antibodies by ELISA and CIA tests in late periods of Trichinella sp invasion

Results of our studies using ELISA and competitive inhibition assay (CIA) t ests fully confirmed the previously experienced trichinellosis and reflecte d persistent stimulation of antibody production due lo the antigen release from Trichinella larvae, which had survived longer and undergone gradual de struction in the muscles. The studies proved that the tests complement each other, yielding concordant results in 86.7 % of cases. Due to its higher s pecificity, the CIA test can help in interpreting pathological signs/sympto ms and in evaluating humoral response activity at late and distant in time periods following the invasion.