The present review of the satiating effect of cholecystokinin in humans has
revealed that cholecystokinin is a physiological satiety factor in humans.
The results demonstrate the efficacy of the satiating actions of exogenous
and endogenous CCK in humans. The therapeutic potential of CCK analogues c
annot be estimated until further studies are performed that demonstrate the
efficacy of CCK analogues for decreasing body weight, and the safety of CC
K when administered repetitively for prolonged periods. (C) 2001 Elsevier S
cience Inc. All rights reserved.