Probing the mechanism of enzymatic phosphoryl transfer with a chemical trick

Authors
Thompson, PR Cole, PA
Citation
Pr. Thompson et Pa. Cole, Probing the mechanism of enzymatic phosphoryl transfer with a chemical trick, P NAS US, 98(15), 2001, pp. 8170-8171
Citations number
25
Categorie Soggetti
Multidisciplinary
Journal title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN journal
00278424 → ACNP
Volume
98
Issue
15
Year of publication
2001
Pages
8170 - 8171
Database
ISI
SICI code
0027-8424(20010717)98:15<8170:PTMOEP>2.0.ZU;2-6
Abstract
A full and convincing explanation at the quantum mechanical level has not b een made as to why dissociative transition states should be preferred for n onenzymatic phosphoryl transfer reactions.