ANTIMUTAGENICITY OF LEMON GRASS (CYMBOPOGON CITRATUS STAPF) TO VARIOUS KNOWN MUTAGENS IN SALMONELLA MUTATION ASSAY

Lemon grass (Cymbopogon citratus Stapf) was extracted with 80% ethanol . The extract was not found to be mutagenic in the Salmonella mutation test with or without metabolic activation. However, the extract was f ound to possess antimutagenic properties towards chemical-induced muta tion in Salmonella typhimurium strains TA98 and TA100. Mutagenicity of AFB(1), Trp-P-1, Trp-P-2, Glu-P-1, Glu-P-2, IQ, MNNG and AF-2, was in hibited by the extract of lemon grass in a dose-dependent manner, but no effect was found on the mutagenic activity of benzo[a]pyrene.