The Pauson-Khand reaction in synthesis of bicyclic rigid alpha-amino acids

Authors
Wang, J Falck-Pedersen, ML Romming, C Undheim, K
Citation
J. Wang et al., The Pauson-Khand reaction in synthesis of bicyclic rigid alpha-amino acids, SYN COMMUN, 31(8), 2001, pp. 1141-1148
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
8
Year of publication
2001
Pages
1141 - 1148
Database
ISI
SICI code
0039-7911(2001)31:8<1141:TPRISO>2.0.ZU;2-1
Abstract
The combination of intramolecular Pauson-Khand methodology for Co-2(CO)(8) mediated cyclization, and the Scholkopf chiral auxiliary for stereoselectiv e preparation of appropriate 1,6-heptenynes constitutes a powerful method f or the preparation of rigidified bicyclic alpha -amino acids.