I. Sylvestre et al., Titanium-mediated diastereoselective formation of (E)-2-alkyl-1-ethenylcyclopropanols from beta-haloesters, TETRAHEDR L, 42(30), 2001, pp. 4991-4994
The titanium(IV)-mediated cyclopropanation of ethyl beta -chloropropionate
by Grignard reagents and in situ tosylation, followed by base-induced dehyd
rochlorination provided diastereoselectivity pure (E)-2-alkyl-1-ethenyl-1-(
tosyloxy)cyclopropanes. suitable precursors of 1,1-ethyleneallylmetal speci
es of significant synthetic potential. (C) 2001 Elsevier Science Ltd. All r
ights reserved.