Diastereoselective synthesis of chiral beta-amino-alpha-hydroxy-H-phosphinates through hydrophosphinylation of alpha-amino aldehydes

Authors
Yamagishi, T Suemune, K Yokomatsu, T Shibuya, S
Citation
T. Yamagishi et al., Diastereoselective synthesis of chiral beta-amino-alpha-hydroxy-H-phosphinates through hydrophosphinylation of alpha-amino aldehydes, TETRAHEDR L, 42(30), 2001, pp. 5033-5036
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
30
Year of publication
2001
Pages
5033 - 5036
Database
ISI
SICI code
0040-4039(20010723)42:30<5033:DSOCB>2.0.ZU;2-X
Abstract
A stereodivergent synthesis of beta -amino-alpha -hydroxy-H-phosphinates wa s achieved by ALB-catalyzed hydrophosphinylation of N,N-dibenzyl-alpha -ami no aldehydes tuning the chirality of the catalyst. (C) 2001 Elsevier Scienc e Ltd. All rights reserved.