Enantioselective reduction of alpha,beta-unsaturated ketones bearing the trifluoromethyl group

Authors
Nenajdenko, VG Smolko, KI Balenkova, ES
Citation
Vg. Nenajdenko et al., Enantioselective reduction of alpha,beta-unsaturated ketones bearing the trifluoromethyl group, TETRAHEDR-A, 12(9), 2001, pp. 1259-1266
Citations number
32
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
9
Year of publication
2001
Pages
1259 - 1266
Database
ISI
SICI code
0957-4166(20010611)12:9<1259:EROAKB>2.0.ZU;2-F
Abstract
alpha,beta -Unsaturated ketones bearing the trifluoromethyl group were enan tioselectively reduced by a variety of reagents to the corresponding second ary allylic alcohols with e.e. in the range 87-99%. The influence of the tr ifluoromethyl group on the enantioselectivity is discussed. (C) 2001 Publis hed by Elsevier Science Ltd.