Synthesis and separation of substituted cyclopropane carboxylic acid amideisomers

Citation
Z. Finta et al., Synthesis and separation of substituted cyclopropane carboxylic acid amideisomers, TETRAHEDR-A, 12(9), 2001, pp. 1287-1292
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
9
Year of publication
2001
Pages
1287 - 1292
Database
ISI
SICI code
0957-4166(20010611)12:9<1287:SASOSC>2.0.ZU;2-P
Abstract
The phase-transfer-catalyzed cyclization of optically active malonic acid a llylic ester amides yields bicyclic cyclopropane carboxamide lactone deriva tives. The two diastereomers obtained could be separated in some cases by s imple column chromatography yielding the pure isomers. (C) 2001 Elsevier Sc ience Ltd. All rights reserved.