Xenotransplantation poses challenges to scientists, ethicists and clinician
s. Recent studies of the role of endogenous retroviruses suggest that these
agents could threaten the safety of porcine xenotransplantation both for t
he recipient of a transplant, and possibly for people who have contact with
that patient. Although the risk of such complications is low, the history
of recent infectious diseases suggests that the precautionary principle sho
uld be invoked.