Preimplantation genetic diagnosis: applications for molecular medicine

Authors
Wells, D Delhanty, JDA
Citation
D. Wells et Jda. Delhanty, Preimplantation genetic diagnosis: applications for molecular medicine, TRENDS MO M, 7(1), 2001, pp. 23-30
Citations number
63
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
TRENDS IN MOLECULAR MEDICINE
ISSN journal
14714914 → ACNP
Volume
7
Issue
1
Year of publication
2001
Pages
23 - 30
Database
ISI
SICI code
1471-4914(200101)7:1<23:PGDAFM>2.0.ZU;2-V
Abstract
Preimplantation genetic diagnosis is an alternative to prenatal diagnosis f or the detection of genetic disorders. Tests are conducted on single cells biopsied from embryos before they are implanted, allowing the selection of unaffected embryos before a pregnancy has been established. Thus, the issue of pregnancy termination is circumvented. The use of preimplantation genet ic diagnosis might have a significant impact on in vitro fertilization succ ess rates as well as allowing the diagnosis of inherited disease.