De helminths play a role in carcinogenesis?

Chronic helminthiasis is recognized as a significant factor in cancer devel opment in humans. However,the mechanisms by which helminths initiate and pr omote malignant transformation of host cells are still not understood fully , Human helminthiasis can cause genetic instability and affect inter- and i ntracellular communication, ultimately leading to tumour development throug h inflammation, modulation of the host immune system, and secretion of solu ble factors that interact with host cells.