Identification of a plasmid encoding SHV-12, TEM-1, and a variant of IMP-2metallo-beta-lactamase, IMP-8, from a clinical isolate of Klebsiella pneumoniae

Authors
Yan, JJ Ko, WC Wu, JJ
Citation
Jj. Yan et al., Identification of a plasmid encoding SHV-12, TEM-1, and a variant of IMP-2metallo-beta-lactamase, IMP-8, from a clinical isolate of Klebsiella pneumoniae, ANTIM AG CH, 45(8), 2001, pp. 2368-2371
Citations number
21
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
45
Issue
8
Year of publication
2001
Pages
2368 - 2371
Database
ISI
SICI code
0066-4804(200108)45:8<2368:IOAPES>2.0.ZU;2-3
Abstract
A multidrug-resistant plasmid encoding TEM-1, SHV-12, and a variant of IMP- 2 metallo-beta -lactamase, designated IMP-8, was identified from a clinical isolate of Klebsiella pneumoniae. There are four nucleotide differences be tween bla(IMP-2) and bla(IMP-8), resulting in two amino acid differences. b la(IMP-8) was also found to be carried by an integron-borne gene cassette s imilar to the bla(IMP-2) cassette.