The secular changes in growth and maturation can be seen as indicators of s
ocio-economic and health status. In most European countries the age of onse
t of puberty and of menarcheal age has been decreasing during the past few
decades. The duration of puberty seems also to decrease, though few studies
provide sufficient data to support this postulation. The four Dutch nation
wide growth surveys are useful examples assessing the secular trend in pube
rtal development over the past 45 years. Genetic and environmental factors
contribute to the secular changes. Environmental factors seem to be the mos
t important. Recently, attention has been given to substances with oestroge
n-like actions that are present in nutrients. The possible role of these su
bstances in growth and maturation is discussed.