Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion

Authors
Voltarelli, JC Ahmed, H Paton, EJA Stracieri, ABPL Holman, P Bashey, A Coutinho, M Simoes, BP Ball, ED Carrier, E
Citation
Jc. Voltarelli et al., Beneficial effect of intravenous lidocaine in cutaneous chronic graft-versus-host disease secondary to donor lymphocyte infusion, BONE MAR TR, 28(1), 2001, pp. 97-99
Citations number
10
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
28
Issue
1
Year of publication
2001
Pages
97 - 99
Database
ISI
SICI code
0268-3369(200107)28:1<97:BEOILI>2.0.ZU;2-3
Abstract
We report two cases of refractory chronic graft-versus-host disease after d onor lymphocyte infusions in which the skin lesions improved dramatically w ith the use of intravenous pulses of lidocaine. This form of therapy has be en used successfully for the cutaneous involvement of scleroderma and may h ave vasodilator and anti-inflammatory effects.