Leiomyosarcomas of vascular origin are a very rare group of tumors developi
ng from smooth vascular muscle cells. The most common location are in large
vessels, e.g. vena cava, saphenous vein or pulmonary artery, but fewer tha
n 200 cases are reported in the literature. We report a case of a patient w
ith a leiomyosarcoma, of the splenic artery. This location has not been des
cribed previously.