Enantioseperation of chiral phenothiazine derivatives in capillary electrophoresis using cyclodextrin type chiral selectors

Authors
Chankvetadze, B Kartozia, I Burjanadze, N Bergenthal, D Luftmann, H Blaschke, G
Citation
B. Chankvetadze et al., Enantioseperation of chiral phenothiazine derivatives in capillary electrophoresis using cyclodextrin type chiral selectors, CHROMATOGR, 53, 2001, pp. S290-S295
Citations number
35
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
CHROMATOGRAPHIA
ISSN journal
00095893 → ACNP
Volume
53
Year of publication
2001
Part
2
Supplement
S
Pages
S290 - S295
Database
ISI
SICI code
0009-5893(2001)53:<S290:EOCPDI>2.0.ZU;2-E
Abstract
The enantioseparation of chiral phenothiazine derivatives has been studied in capillary electrophoresis (CE) using various cyclodextrins (CD) such as native alpha, beta, and gamma -CD and some of their neutral and charged der ivatives. Comparative binding studies were performed using nuclear magnetic resonance (NMR) spectrometry. The advantages and disadvantages of the bind ing parameters obtained in both techniques (NMR and CE) from the viewpoint of separation optimization are discussed.