Effects of minor constituents (non-glyceride compounds) of virgin olive oil on plasma lipid concentrations in male Wistar rats

We aimed to assess the effects of minor constituents (MC) from virgin olive oil upon the plasma lipid profile of experimental animals. Therefore, 32 W istar rats were fed for 6 weeks with one of four different diets with a sim ilar fatty acid composition but different MC: high-oleic sunflower ail (HOS O), virgin olive oil (VOO), 400%-MC enriched olive oil (EOO) and MC poor (i mpoverished) olive oil (IOO). At the end of the week 6 of dietary treatment , blood samples were obtained for analysis of lipid composition. A statisti cally significant influence was observed upon both total HDL (1.593 +/- 0.4 , 1.204 +/- 0.212, 0.991 +/- 0.244 and 0.827 +/- 0.279 mmol/L for EOO, HOSO , VOO and IOO, respectively, Kruskal-Wallis test, P < 0.05) and HDL2 choles terol levels (1.16 +/- 0.26, 0.576 +/- 0.191, 0.585 +/- 0.216 and 0.583 +/- 0.207 mmol/L for EOO, HOSO,VOO and IOO, respectively, Kruskal-Wallis test, P < 0.05). No statistically significant effect was observed upon LDL-chole sterol or triglycerides. Thus, MC supplementation has beneficial effects on HDL concentrations in Wistar rats. (C) 2001 Harcourt Publishers Ltd.