Vertebrate limb development - the early stages in chick and mouse

Citation
C. Tickle et A. Munsterberg, Vertebrate limb development - the early stages in chick and mouse, CUR OP GEN, 11(4), 2001, pp. 476-481
Citations number
37
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN GENETICS & DEVELOPMENT
ISSN journal
0959437X → ACNP
Volume
11
Issue
4
Year of publication
2001
Pages
476 - 481
Database
ISI
SICI code
0959-437X(200108)11:4<476:VLD-TE>2.0.ZU;2-R
Abstract
More news this year about FGFs and their roles in vertebrate limb initiatio n; Writ signalling is shown for the first time to be another component of t he signalling cascade involved in early limb formation. Ectodermal compartm ents that control apical ridge formation were previously described in chick embryos and are now shown to exist in mouse embryos; Engrailed1 is express ed in the ventral ectodermal compartment but experiments in both chick and mouse show that it is not responsible for compartment specification.