Obesity has long been suspected as predisposing to gastroesophageal reflux
disease, and it has also been claimed that it is an important cause of poor
outcome following laparoscopic anti-reflux surgery. This study was perform
ed to determine the validity of this proposition. The outcome of 194 patien
ts from an overall experience of 971 laparoscopic anti-reflux procedures wa
s determined in this study. Patients were included if they had undergone a
laparoscopic Nissen fundoplication, had completed a minimum 12 months follo
w-up using a structured questionnaire, and had data available for the calcu
lation of their preoperative body mass index (BMI). Patients were divided i
nto three groups based on BMI: normal weight (BMI < 25), overweight (BMI 25
-29.9), and obese (BMI > 30). The association between BMI and outcome data
from their most recent follow-up was analyzed. There was no correlation bet
ween increasing BMI and a poorer overall outcome. There was a slight trend
toward less satisfaction with the surgical outcome in patients of normal we
ight. Preoperative obesity is not associated with a poorer outcome followin
g laparoscopic Nissen fundoplication.