New cyclodextrin derivatives as chiral selectors in capillary electrophoresis

The separation of three pairs of enantiomeric herbicides has been successfu lly achieved by capillary electrophoresis at two different pH values in the presence of cyclodextrin derivatives previously synthesized in our laborat ory. Two of these derivatives constitute a new class of receptor, the hemis pherodextrins, in which a trehalose capping moiety is bonded to beta -cyclo dextrin. Because of their peculiar structure hemispherodextrins have very p romising characteristics and the low receptor concentration required to ach ieve separation deserves particular interest.