Fa. Abu-shanab et al., Enaminones as bulding blocks in organic synthesis: Synthesis of new polyfunctional pyridines, condensed pyridines and penta substituted benzene., HETEROCYC C, 7(2), 2001, pp. 183-192
Compound la reacted with phenacylbromide and chloroacetamide to yield thien
opyridine derivatives 6 and 7. Compound 1b reacted with DMFDMA to yield met
hylthioether 3 which reacted with DMFDMA to yield pyridine derivative 4. Co
mpound 7 reacted with DMFDMA to yield pyrido[2,3-b]thieno[3,2-d]pyrimidine
derivative 10. Compounds 2a and 2b reacted with malononitrile to afford pyr
idone derivative 11 and pyrane 13. Compound 2c reacted with cyanoacetamide
to yield pentasubstituted benzene 16.