Morphological changes of vestibular ganglion cells in human fetuses and inpediatric patients

The temporal bone histopathology of human vestibular ganglion cells of fetu ses and pediatric patients was studied. In the first study, we traced the m orphological changes in vestibular ganglion cells ill human fetuses ranging from 13 weeks to 39 weeks of gestational age by using 13 temporal bone ser ial sections. Vestibular ganglion cells had reached histological maturity b y the 24th week of gestation and the volume of vestibular ganglion cell cyt oplasm increased until the 39th week of gestation. In the second study, the temporal bone serial sections of seven neonates, eight infants and five ch ildren were investigated to reveal pathological changes in vestibular gangl ion cells. Morphological changes in vestibular ganglion cells in human fetu ses were revealed. Vestibular ganglion cells were changed pathologically by intracranial disease and variety etiology affecting the inner ear, because these are located in the internal auditory canal between the brain and lab yrinth. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.