Exhaustive generation of organic isomers. 6. Stereoisomers having isolatedand spiro cycles and new extended N_tuples

A new stereoisomer generation system named CAMGEC2 for generation of stereo isomers containing isolated and spiro cycles with one or more descriptors a mong R, S, Z, E, M, and P is developed using Graph Theory. It includes new approaches for symmetry analysis, cycle detection processes in molecular gr aphs in a modular way, and also an extension of the N_tuple format for line ar representation of molecular graphs that keeps graph topographical inform ation.