Background: Epidermal necrosis in a neonate is an uncommon event with a var
iety of potential cases.
Result: We report a case of intrauterine epidermal necrosis in a preterm in
fant, with death occurring soon after birth. The histopathology of the denu
ded skin revealed full-thickness epidermal necrosis and calcification withi
n both the epidermis and follicular structures.
Conclusion: We believe this represents the fourth reported case of lethal i
ntrauterine epidermal necrosis and follicular calcification.