Citation
B. Caronti et al., Dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease, J NEURAL TR, 108(7), 2001, pp. 803-807
Citations number
12
Categorie Soggetti
Neurosciences & Behavoir
Journal title
JOURNAL OF NEURAL TRANSMISSION
ISSN journal
03009564
→ ACNP
Volume
108
Issue
7
Year of publication
2001
Pages
803 - 807
Database
ISI
SICI code
0300-9564(2001)108:7<803:DTIIPB>2.0.ZU;2-H
Abstract
There is increasing interest in the identification of biological markers fo
r the early diagnosis of Parkinson's disease (PD). Previous studies indicat
e changes of dopamine content, tyrosine hydroxylase immunoreactivity and do
pamine receptors in peripheral blood lymphocytes (PBL) in PD. Here we demon
strate a reduction of dopamine transporter immunoreactivity in PBL in the e
arly clinical stages of the disease. These findings contribute to our under
standing of the peripheral dopamine system in PD.