An unusual case of a 62-year-old man with focal seizures, tinnitus, and pro
gressive left hemiparesis due to an extensive subdural plasma cell granulom
a is presented. Five-year clinical and radiologic follow-up demonstrating t
he chronic yet progressive nature of this granuloma is presented. This is t
he first report of focal calcification seen in an intracranial plasma cell
granuloma. The imaging, neuropathologic, and clinical characteristics of th
is rare lesion are reviewed.