D. Wengrower et al., CROHNS-DISEASE IN LATE ADOLESCENCE - ACUTE ONSET OR LONG-STANDING DISEASE, Journal of clinical gastroenterology, 24(4), 1997, pp. 224-226
We studied retrospectively a group of 53 patients with Crohn's disease
, diagnosed between 18 and 21 years of age. They had all undergone a t
horough medical evaluation at age 17 before military service. They thu
s served as a unique group in whom the natural course of the disease,
duration of signs and symptoms before diagnosis, and delay in diagnosi
s could be assessed. Other than a more frequently elicited history of
nonspecific mild recurrent abdominal pain in childhood in the patient
group, medical history, physical growth, sexual development, and labor
atory parameters of inflammation did not differ in the patient group a
nd the healthy control group. Crohn's disease in this group of young a
dults is likely one of acute onset and did not begin as an exacerbatio
n of a more subtle and prolonged process.