Preventing antiretroviral anarchy in sub-Saharan Africa

Combination antiretroviral therapy has dramatically improved the survival o f patients living with HIV and AIDS In Industrialised countries of the worl d. Despite this enormous benefit, there are some major problems and obstacl es to be overcome.(1) Treatment of HIV-infection is likely to be lifelong.( 2) Unfortunately, many HIV-Infected individuals cannot tolerate the toxic e ffects of the drugs, or have difficulty complying with treatment which invo lves large numbers of pills and complicated dosing schedules. Poor adherenc e to treatment leads to the emergence of drug-resistant viral strains that need new combinations of drugs or new drugs altogether.