Low-grade non-Hodgkin's lymphoma in a patient with systemic lupus erythematosus

Citation
T. Robak et al., Low-grade non-Hodgkin's lymphoma in a patient with systemic lupus erythematosus, LEUK LYMPH, 41(5-6), 2001, pp. 659
Citations number
29
Categorie Soggetti
Hematology,"Onconogenesis & Cancer Research
Journal title
LEUKEMIA & LYMPHOMA
ISSN journal
10428194 → ACNP
Volume
41
Issue
5-6
Year of publication
2001
Database
ISI
SICI code
1042-8194(200105)41:5-6<659:LNLIAP>2.0.ZU;2-A
Abstract
Coexistence of systemic lupus erythematosus (SLE) with low-grade non-Hodgki n's lymphoma (LGNHL) has been described occasionally in the literature with the potential pathogenetic role of monoclonal B CD5+/CD19+ cells. We repor t a case of LGNHL which developed 18 months after diagnosis of SLE. The mon oclonal population of lymphocytes ia the peripheral blood and bone marrow w as CD5/CD19 negative but CD19/CD22 positive. The SLE responded well to trea tment with prednisone and the course of the LGNHL was stable and cytotoxic treatment was not required.