STEREOCONTROLLED SYNTHESIS OF (E,E,E)-CHLOROTRIENES - EFFICIENT INTERMEDIATES FOR THE CONSTRUCTION OF ALL E-CONJUGATED POLYENES

Authors
CROUSSE B ALAMI M LINSTRUMELLE G
Citation
B. Crousse et al., STEREOCONTROLLED SYNTHESIS OF (E,E,E)-CHLOROTRIENES - EFFICIENT INTERMEDIATES FOR THE CONSTRUCTION OF ALL E-CONJUGATED POLYENES, Tetrahedron letters, 38(30), 1997, pp. 5297-5300
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
30
Year of publication
1997
Pages
5297 - 5300
Database
ISI
SICI code
0040-4039(1997)38:30<5297:SSO(-E>2.0.ZU;2-M
Abstract
Stereoselective reduction of conjugated homopropargylic alcohols 1 fol lowed by an elimination reaction, allows an efficient approach to ster eodefined (E,E,E)-chlorotrienes. The interest of these chlorotrienes w as illustrated by a stereocontrolled synthesis of navenone B and all E conjugated polyenes (trienes, tetraenes and hexaenes). (C) 1997 Publi shed by Elsevier Science Ltd.