Objectives: To establish the frequency and severity of somatic symptoms and
emotional distress (anxiety and/or depression) among our chronic hemodialy
sis (CHD) patients and to study the relationship between them as well as th
eir influence on the perceived health status.
Patients and methods: All patients who had been on CHD for a minimum of thr
ee months were eligible for the study. Eight of them were excluded: six bec
ause they were unable to answer the questionnaires and two because they ref
used to participate. The 58 remaining patients were the subject of our stud
y (median age 68.5 years; median duration of HD 29.5 months). Diverse socio
demographic and clinical data were recorded. The patients answered the foll
owing questionnaires: I) The physical symptoms,, dimension of the Kidney Di
sease Questionnaire; 2) A measure of anxiety (STAI); 3) A measure of depres
sion (Beck Depression Inventory and Cognitive Depression Index); and 4) The
Nottingham Health Profile (NHP).
Results: The most frequent and severe symptoms were tiredness, itching, thi
rst, bone and joint pain and sleep disturbance. The severity of the symptom
s was positively associated with female sex, and the presence of clinically
relevant degrees of anxiety and/or depression. A quarter of the patients w
ere anxious and almost half of them suffered from depression. Emotional dis
turbances were associated with the severity of somatic symptoms and comorbi
dity. Only anxiety and depression were significantly associated with the gl
obal NHP score; they explained 47% of its variance. A score of 50 or more i
n the "Emotional Reactions" dimensions with the NHP detected 69% of the pat
ients with anxiety and 81% of those with depression.
Conclusions: Somatic symptoms are common among patients on CHD and they app
ear to be associated with emotional distress (anxiety and depression) that
influences significantly the perceived health status. Measuring the perceiv
ed health status by means of generic and specific questionnaires, may help
to establish the diagnosis of these problems.