Combination of tert-butoxycarbonyl and triphenylphosphonium protecting groups in the synthesis of substituted hydrazines

[GRAPHICS] A new reagent for the systematic synthesis of substituted hydrazines is rep orted. Unlike previously developed reagents, this one contains only two pro tecting groups, thus providing a faster approach to multisubstituted deriva tives. The selective introduction of alkyl and acyl groups is illustrated b y a few examples, Also a new fast method for the deprotection of the triphe nylphosphonium group is presented.