Influence of HMPA on reducing power and reactivity of SmBr2

Authors
Knettle, BW Flowers, RA
Citation
Bw. Knettle et Ra. Flowers, Influence of HMPA on reducing power and reactivity of SmBr2, ORG LETT, 3(15), 2001, pp. 2321-2324
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
15
Year of publication
2001
Pages
2321 - 2324
Database
ISI
SICI code
1523-7060(20010726)3:15<2321:IOHORP>2.0.ZU;2-Q
Abstract
[GRAPHICS] Addition of HMPA to SmBr2 in THF produces a reactant with an estimated redo x potential of -2.63 +/- 0.01 V (vs AS/AgNO3), This powerful reductant is c apable of reducing ketimines and alkyl chlorides at room temperature. Altho ugh the structure of the reductant has not been established, it is nonethel ess a powerful addition to the arsenal of samarium based reductants current ly utilized.