Asymmetric dihydroxylation of olefins using cinchona alkaloids on highly ordered inorganic supports

Authors
Motorina, I Crudden, CM
Citation
I. Motorina et Cm. Crudden, Asymmetric dihydroxylation of olefins using cinchona alkaloids on highly ordered inorganic supports, ORG LETT, 3(15), 2001, pp. 2325-2328
Citations number
42
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
15
Year of publication
2001
Pages
2325 - 2328
Database
ISI
SICI code
1523-7060(20010726)3:15<2325:ADOOUC>2.0.ZU;2-I
Abstract
[GRAPHICS] A modified cinchona alkaloid was grafted onto a mesoporous molecular sieve and onto amorphous silica gel. These heterogeneous ligands were employed in the asymmetric dihydroxylation of olefins under Sharpless conditions. The supported ligands yielded equivalent enantioselectivity compared with that of the homogeneous system and were easily recovered and reused.