We conducted a case-control study to examine the efficacy of non-stress tes
ting in preventing fetal death in post-term pregnancy. The analysis was bas
ed on data from the 1988 National Maternal and Infant Health Survey, which
was a nationally representative sample of live births, fetal deaths and inf
ant deaths that occurred in 1988. Information on whether a woman had non-st
ress testing was obtained from a questionnaire sent to prenatal care provid
ers and hospitals. Cases were post-term women (with 42 weeks or more gestat
ion) who had fetal deaths. Three post-term controls, who had live births an
d who delivered at the same time or later than the cases, were randomly cho
sen and individually matched to each case by maternal race. The proportion
of women who had one or more non-stress tests during pregnancy was compared
between cases and controls. Non-stress testing was used in 30.9% of the 12
6 cases and in 28.5% of the 375 controls. The race-adjusted odds ratio for
exposure to non-stress test was 1.12 [95% CI 0.72, 1.75]. After controlling
for other important confounding variables the odds ratio was 1.05 [95% CI
0.57, 1.91]. These results do not support the efficacy of non-stress testin
g in post-term pregnancies. A more detailed evaluation of this widely used
screening procedure is needed.