Psychiatric disorders before and after living-related transplantation

The authors examined psychiatric disorders among two samples of patients wh o underwent living-related transplant (LRT) for kidney and liver failure, T he postoperative prevalence of psychiatric disorders for adult transplant r ecipients was highest the first 3 months posttransplant. The incidence of p sychiatric disorders in the adult recipients with living-related liver tran splant (LRLT) was higher (54%, 22 of 41) than that of adult recipients with living-related kidney transplant (LRKT) (28%, 65 of 234). Twelve (80%) of the 15 adult LRLT recipients with adult child-to-parent donors exhibited pa radoxical psychiatric syndrome (PPS). Among the 12 affected recipients, gui lt-based psychiatric disorders of various types occurred despite successful operative outcome for both donor and recipient. The higher rate of psychia tric disorders among adult LRLT recipients was associated with the occurren ce of PPS among recipients of tin adult-child allograft. These results sign al a new challenge for consultation psychiatrists working with transplant p atients.