Gabapentin for the treatment and prophylaxis of cluster headache

Background and Objectives: Cluster headache is an uncommon debilitating con dition for which effective management remains a challenge. We describe the use of gabapentin in the treatment and prophylaxis of cluster headache in a patient who was refractory to other treatments. Case Report: A 38-year-old man had a history of intermittent right-side hea daches for 24 years, diagnosed as cluster headache. He received only partia l relief from a range of conventional treatments. A trial with gabapentin 3 00 mg twice daily was tried and found to be effective in treatment and prop hylaxis of his headaches. Conclusion: Gabapentin was effective in the treatment of a patient with clu ster headache. Further investigation of gabapentin compared with convention al treatments and placebo is warranted.