IMAGE REGISTRATION OF MR AND CT IMAGES USING A FRAMELESS FIDUCIAL MARKER SYSTEM

A new system of fiducial stereotactic markers that can easily be adapt ed to various imaging modalities without losing image registration was developed and tested. Utilizing MR and CT imaging the accuracy of the new system was evaluated with phantom studies and preliminary patient studies. The markers are clearly visible without artifacts on both im aging modalities. The clear delineation of the marker dots on the imag es enables an accurate automated marker detection. Using the marker sy stem, image registration was found to yield an accuracy of up to 1 mm, depending on the imaging modality and the employed marker arrangement . The presented marker system shall improve patient comfort in compari son to conventional fixed stereotactic frames if repeated, highly accu rate registrations are necessary over longer periods. (C) 1997 Elsevie r Science Inc.