A fungus among us: the Neurospora crassa circadian system

Citation
M. Merrow et al., A fungus among us: the Neurospora crassa circadian system, SEM CELL D, 12(4), 2001, pp. 279-285
Citations number
62
Categorie Soggetti
Cell & Developmental Biology
Journal title
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
ISSN journal
10849521 → ACNP
Volume
12
Issue
4
Year of publication
2001
Pages
279 - 285
Database
ISI
SICI code
1084-9521(200108)12:4<279:AFAUTN>2.0.ZU;2-F
Abstract
Neurospora crassa is the only molecular genetic model system for circadian rhythms research in the fungi. Its strengths as a model organism lie in its relative simplicity-compared to photosynthesizing and vertebrate organisms , it is a stripped-down version of life. It forms syncitial hyphae, propaga tes and reproduces, and the circadian clock is manifest in numerous process es therein. As with other model circadian systems, Neurospora features a tr anscription/translation feedback loop that is fundamental to an intact circ adian system. The molecular components of this loop converge with those of blue light photoreception, thus bringing the clock and one of its input pat hways together.