Objectives: This report documents the prevalence of hepatitis C virus (HCV)
infection among self-reported noninjecting drug users recruited from two N
ew York City neighborhoods. Methods: Participants were recruited in separat
e studies from East Harlem and the Lower East Side of Manhattan and were ad
ministered structured questionnaires and tested for HCV. Results: HCV preva
lence rates among those reporting no history of injecting drugs ranged from
5% to 29%, according to age, gender, and study location. Conclusions: Our
results suggest that more research is needed to elucidate potential noninje
cting routes of HCV transmission among drug users, Moreover, policies that
rely predominantly on injector status as the only drug-related risk factor
for HCV screening need to be reassessed in light of these findings.