Residence appears to exert influence over choices of venues for injection a
mong intravenous drug users (IDUs) in Valencia, Spain. While living in thei
r parents' homes, young IDUs may resort to high-risk venues for injection,
particularly chutaderos in which used needles and syringes are often reused
. Residence patterns of young IDUs in Spain may be highly similar to reside
nce of IDUs in Italy and Puerto Rico, which also have AIDS epidemics domina
ted by IDUs rather than men who have sex with men. Intervention in these pl
aces needs to take contextual factors of residence into account for effecti
ve prevention of HIV infection.