Preparation, characterization, and thermodynamic studies of Promazine, Chlorpromazine, Promethazine, Imipramine, and Ciprofloxacin ion-associates with some metal complex ions

The ion-associate complexes of Promazine (Prom.Cl), Chlorpromazine (Chlorpr om.Cl), Promethazine (Prometh.Cl), Imipramine (Imip.Cl) and Ciprofloxacin ( Cipro.Cl) hydrochlorides with potassium ferricyanide, ammonium reineckate a nd sodium cobaltinitrite have been prepared. The precipitated ion-associate s were subjected to elemental analyses, infrared spectral studies, thermogr avimetric analysis and determination of the metal content for elucidation o f their structures. The solubilities of the solid ion-associate complexes h ave been studied and their solubility products were determined at different temperatures at the optimum conditions of pH and ionic strength for their quantitative precipitation. The thermodynamic parameters DeltaH, DeltaG and DeltaS for the dissolution of the ion-associate complexes were calculated.